吴谦预聘副教授

深圳北理莫斯科大学副教授、硕士生导师。2013年获得华中科技大学同济医学院药学院药学学士学位，于2018年获得北京大学化学（化学基因组学）博士学位，随后加入深圳大学AIE研究中心唐本忠院士团队进行博士后研究。2021-2023年在香港科技大学唐本忠院士课题组进行博士后研究。截至目前已在Nature  Communications，Matter，Advanced  Functional  Materials，Biomaterials等国际期刊公开发表SCI收录文章30余篇，主持结题国自然青年基金和博士后面上项目。研究兴趣为聚集诱导发光全新发光结构的设计与合成，发光机理的研究和在智能传感、生物诊疗等方向的应用。

■ Biography-Short  Description

Qian Wu is currently an  associate professor and master  supervisor at Shenzhen MSU-BIT  University. Prof. Wu received  her Ph.D. in organic chemistry  from Peking University in 2018.  Then she joined the Shenzhen  university (2018-2021) and Hong  Kong University of Science and  Technology (2021-2024) as the  post-doctor. She has been the  project leader of funding,  including the Youth Fun  supported by the National  Natural Science Foundation of  China, and China Postdoc  Foundation. Prof. Wu has  published over 30 papersin top  journals such as Nature  Communications, Matter, Advanced  Functional Materials,  Biomaterials etc.

■ 教育经历

□ 2009.09-2013.07  华中科技大学同济医学院药学院基地班，生物药学，学士;

□ 2013.09-2018.07  北京大学，化学(化学基因组学)，博士.
 

■ 工作经历

□ 2018.10-2021.04 深圳大学  材料学院AIE研究中心 博士后;
□ 2019.03-2020.03 香港科技大学 化学系  访问学者;
□2021.07-2024.08 香港科技大学 化学系 博士后;
□ 2024.09-当前 深圳北理莫斯科大学 材料科学系  副教授.
 

■ 研究领域

■ Research  Interest

Theoretical design and  construction of new luminogens  with Aggregation-induced  emission characteristics for  organic light-emitting diode,  chemical sensor, biological  imaging and therapy.

■ 主讲课程

无

■ 社会兼职

无

■  荣誉奖励

□  Aggregate 杂志优秀贡献奖；

□ 香港政府创新科技基金博士后人才计划；

□ 北京大学优秀博士论文.

■ 科研工作

□  国家自然科学基金青年科学基金项目，基于介离子的新型有机室温磷光材料的构建与性能研究,  2020-2022，项目负责人，已结题；
□  中国博士后科学基金面上项目，一种新型介离子聚集诱导发光分子的构建与性能研究,  2019-2021，项目负责人，已结题；
□  国家自然科学基金面上项目，近红外二区光激发的聚集诱导发光探针的制备及其在荧光-光声双模态肿瘤成像中的应用研究,  2022-2025，项目骨干；
□  国家自然科学基金面上项目，用于细菌介导肿瘤诊疗的近红外荧光体系的构建及应用研究,  2023-2026，项目骨干.

■代表性成果（论文 ）

1. Qian Wu, Junkai Liu, Youmei Li,  Michelle M. S. Lee, Lianrui Hu,  Ying Li, Panwang Zhou, Dong  Wang* and Ben Zhong Tang*, Janus  luminogens with bended  intramolecular charge transfer:  towards molecular transistor and  brain imaging, Matter 2021, 4, 3286-3300.  (IF=19.967)

2. Youmei Li^#, Qian Wu^#,  Dan Li, Jiachang Huang, Haifei  Wen, Yi Wu, Dong Wang* and Ben  Zhong Tang*, A nanotheranostic  system combining lysosomal cell  death and nuclear apoptosis  functions for synergistic cancer  therapy and addressing drug  resistance, Adv. Funct.  Mater. 2021, 31,  2106091. (IF= 19.924)

3. Qian Wu, Youmei Li, Ying Li*, Dong  Wang* and Ben Zhong Tang*,  Hydrogen peroxide-responsive AIE  probe for imaging-guided  organelle targeting and  photodynamic cancer cell  ablation, Mater. Chem. Front. 2021, 5, 3489-3496.  (IF= 8.683)

4. Qian Wu, Youmei Li, Lei Wang, Dong  Wang* and Ben Zhong Tang*,  Aggregation-induced emission: An  emerging concept in brain  science, Biomaterials 2022, 286, 121581. (IF=  15.304)

5. Haoran Wang,* Qian Wu,* and Jong Seung  Kim*, A case study: From  reductionism to holism, Chem  2024, 10, 2345.

6. Qian Wu^#, Dingyuan Yan^#,  Ying Chen^#, Ting  Wang, Feng Xiong, Wei Wei, Yi  Lu, Wei-Yin Sun, Jie Jack Li and  Jing Zhao*, A redox-neutral  catechol synthesis, Nat.  Commun. 2017, 8,  14227. (IF= 17.694)

7. Qian Wu, Ying Chen, Dingyuan Yan,  Muyue Zhang, Yi Lu, Wei-Yin Sun  and Jing Zhao*, Unified  synthesis of mono/bis-arylated  phenols via Rh(III)-catalyzed  dehydrogenative coupling, Chem. Sci. 2017, 8,  169.

8. Michelle M. S. Lee, Qian Wu, Joe H. C.  Chau, Wenhan Xu, Eric Y. Yu,  Ryan T. K. Kwok*, Jacky W. Y.  Lam, Dong Wang* and Ben Zhong  Tang*, Leveraging bacterial  survival mechanism for targeting  and photodynamic inactivation of  bacterial biofilms with red  natural AIEgen. Cell Reports  Physical Science 2022, 3,  100803.

9. Dingyuan Yan, Qian Wu, Dong Wang* and  Ben Zhong Tang*, Innovative  synthetic protocols for  aggregation-induced emission  luminogens: Recent advances and  prospects, Angew. Chem. Int.  Ed. 2021, 60,  15724-15742.

10. Dingyuan Yan^#, Miao Wang^#,  Qian Wu, Niu Niu, Meng Li,  Ruixiang Song, Jie Rao, Miaomiao  Kang, Zhijun Zhang, Feifan  Zhou*, Dong Wang* and Ben Zhong  Tang*, Multimodal imaging-guided  photothermal immunotherapy based  on a versatile NIR-II  aggregation-induced emission  luminogen, Angew. Chem. Int.  Ed. 2022, 61,  e202202614.

11. Dan Li^#, Youmei Li^#,  Qian Wu, Peihong Xiao, Lei Wang,  Dong Wang* and Ben Zhong Tang*,  Add the finishing touch:  molecular engineering of  conjugated small molecule for  high-performance AIE luminogen  in multimodal phototheranostics, Small 2021, 17,  2102044.

12. Youmei Li, Qian Wu, Miaomiao Kang, Nan  Song, Dong Wang* and Ben Zhong  Tang*, Boosting the photodynamic  therapy efficiency by using  stimuli-responsive and  AIE-featured nanoparticles. Biomaterials 2020, 232,  119749.

13. Kang Wang, Saisai Yan, Ting Han*, Qian  Wu, Neng Yan, Miaomiao Kang,  Jinyin Ge, Dong Wang*, and Ben  Zhong Tang*, Cascade  C–H-activated polyannulations  toward ring-fused heteroaromatic  polymers for intracellular pH  mapping and cancer cell killing, J. Am. Chem. Soc. 2022, 144, 11788-11801.

14. Shanliang Song, Yajun Wang, Yue Zhao,  Wenbin Huang, Fei Zhang, Shoujun  Zhu*, Qian Wu, Shuang Fu, Ben  Zhong Tang * and Dong Wang*,  Molecular engineering of AIE  luminogens for NIR-II/IIb  bioimaging and surgical  navigation of lymph nodes, Matter 2022, 5, 1-17.

15. Shanliang Song, Yue Zhao, Miaomiao  Kang*, Zhijun Zhang, Qian Wu,  Shuang Fu, Youmei Li, Haifei  Wen, Dong Wang* and Ben Zhong  Tang*, Side-chain engineering of  aggregation-induced emission  molecules for boosting cancer  phototheranostics, Adv.  Funct. Mater. 2021, 31,  2107545.

16. Wei Zhu, Miaomiao Kang, Qian Wu,  Zhijun Zhang, Yi Wu, Chunbin Li,  Kai Li*, Lei Wang, Dong Wang*  and Ben Zhong Tang*,  Zwitterionic AIEgens: Rational  molecular design for NIR-II  fluorescence imaging-guided  synergistic phototherapy. Adv. Funct. Mater. 2021, 31, 2007026.

17. Meng Li, Huan Li, Qian Wu, Niu Niu,  Jiachang Huang, Lingmin Zhang,  Ying Li*, Dong Wang* and Ben  Zhong Tang*, Hypoxia-activated  probe for NIR fluorescence and  photoacoustic dual-mode tumor  imaging, iScience 2021,  24, 102261.

18. Miaomiao Kang, Zhijun Zhang, Wenhan  Xu, Haifei Wen, Wei Zhu, Qian  Wu, Hongzhuo Wu, Dong Wang* and  Ben Zhong Tang*, Good steel used  in the blade: Well-tailored  type-I photosensitizers with  aggregation-induced emission  characteristics for precise  nuclear targeting photodynamic  therapy, Adv. Sci. 2021, 8, 2100524.

19. Haifei Wen, Zhijun Zhang*, Miaomiao  Kang, Haoxuan Li, Wenhan Xu,  Heng Guo, Youmei Li, Yonghong  Tan, Ziyao Wen, Qian Wu,  Jiachang Huang, Lei Xi, Kai Li,  Lei Wang, Dong Wang* and Ben  Zhong Tang*, One-for-all  phototheranostics: single  component AIE dots as  multi-modality theranostic agent  for fluorescence-photoacoustic  imaging-guided synergistic  cancer therapy, Biomaterials 2021, 274, 120892.

20. Peihong Xiao#, Ke Ma#, Miaomiao Kang,  Luyi Huang, Qian Wu, Nan Song,  Jinyin Ge, Dan Li, Jianxia Dong,  Lei Wang, Dong Wang* and Ben  Zhong Tang*, An  aggregation-induced emission  platform for efficient Golgi  apparatus and endoplasmic  reticulum specific imaging, Chem. Sci. 2021, 12,  13949-13957.

21. Wei Zhu, Ke Ma, Zhi-Chao Yan*, Qian  Wu, Dong Wang* and Ben Zhong  Tang*, DNA tetrahedron-loaded  natural photosensitizer with  aggregation-induced emission  characteristics for boosting  fluorescence imaging-guided  photodynamic therapy, Mater.  Chem. Front. 2021, 5,  5410-5417.

22. Ting Han, Dingyuan Yan, Qian Wu, Nan  Song, Haoke Zhang, Dong Wang*,  Aggregation-induced emission: A  rising star in chemistry and  materials science, Chin. J.  Chem. 2021, 39, 677-689.

23. Deliang Wang, Hongzhuo Wu, Junyi Gong,  Yu Xiong*, Qian Wu, Zheng Zhao,  Lei Wang, Dong Wang* and Ben  Zhong Tang*, Unveiling the  crucial contributions of  electrostatic and dispersion  interactions to the ultralong  room-temperature phosphorescence  of H-bond crosslinked poly(vinyl  alcohol) films, Mater. Horiz. 2022,  Doi:10.1039/D1MH01829A.

24. Hanchen Shen, Changhuo Xu, Feiyi Sun,  Mengying Zhao, Qian Wu, Jianyu  Zhang, Sijie Li, Jing  Zhang*, Jacky W. Y. Lam*, Ben Zhong  Tang*, Metal-based  aggregation-induced emission  theranostic systems, ChemMedChem 2022, 17,  e202100578.

25. Bing Liu^#, Yong Wang^#,  Ying Chen, Qian Wu, Jing Zhao*  and Jianwei Sun*,  Stereoselective synthesis of  fully-substituted acrylonitriles  via formal acylcyanation of  electron-rich alkynes. Org.  Lett. 2018, 20, 3465.

26. Feng Xiong, Liang Lu, Tian-Yu Sun,  Qian Wu, Dingyuan Yan, Ying  Chen, Xinhao Zhang, Wei Wei, Yi  Lu, Wei-Yin Sun, Jie Jack Li and  Jing Zhao*, A bioinspired and  biocompatible ortho-sulfili-minylphenol  synthesis, Nat. Commun. 2017, 8, 15912.

27.  Yiyong Yan, Ling  Zhang, Qian Wu, Zhuwen Chen,  Chao Yang, Jian Zhang, Mengying  Yu and Jing Zhao*, The small  molecule optical probes for  gases with potential medical  application, Sci. China Chem.  2015, 8, 812.